Both egg and sperm cells start life as primordial germ cells (PGCs). Last year, Katsuhiko Hayashi and his colleagues at Kyoto University in Japan found they could generate PGC-like cells from either mouse embryonic stem cells or body cells that can turn into stem cells – known as induced pluripotent stem cells or IPSCs. What’s more, the team managed to coax these PGC-like cells into becoming sperm (Cell, DOI: 10.1016/j.cell.2011.06.052).
Now Hayashi and his colleagues have created eggs from the PGC-like cells. They started with embryonic stem cells and IPSCs taken from a female mouse embryo. In separate experiments, the team coaxed each type of stem cell to form PGC-like cells. When these cells were surrounded by ovary cells, also taken from a mouse embryo, they formed immature egg cells. … >>Continue<<
Source and Photo: NewScientist, October 4th, 2012
You also follow Labex Korea by Twitter